ro 4 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2087	AF-353	Ro-4	P2X Receptor
	AF-353 (Ro-4), an effective and orally bioavailable antagonist of the P2X3/P2X2/3 receptor, inhibits human and rat P2X3 (pIC50= 8.0).		P2X Receptor
T3559	4-Oxoisotretinoin	Oxoretinoic acid,4-Oxoisotretinoin,Ro 22-6595	Others
	4-Oxoisotretinoin (Ro 22-6595) is the major blood metabolite.		Others
T12745L	(4R)-RO5263397		Others
	(4R)-4-(3-Fluoro-2-methylphenyl)-4,5-dihydro-2-oxazolamin was active against TRACE AMINE ASSOCIATED RECEPTOR (TAAR 1) with an EC50 of 0.017 μM and could be used to study neurological disorders.		Others
T34361	Ro 4-6824	AI3-50843
	Ro 4-6824 is a biochemical with immunosuppressive action.
T8139	Sulfamethoxazole sodium	Ro 4-2130 sodium	Others , Antibacterial , Antibiotic
	Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibiotic		Others , Antibacterial , Antibiotic
T1517	Benserazide hydrochloride	Benserazide HCl,Serazide,Ro 4-4602	Dopamine Receptor
	Benserazide hydrochloride (Ro 4-4602) is a peripherally-acting L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.		Dopamine Receptor
T0885	Sulfamethoxazole	Ro 4-2130,STX 608	Antibacterial , Antibiotic , Autophagy
	Sulfamethoxazole (STX 608) is a Sulfonamide Antimicrobial. The mechanism of action of sulfamethoxazole is as a Cytochrome P450 2C9 Inhibitor. The chemical classification of sulfamethoxazole is Sulfonamides.		Antibacterial , Antibiotic , Autophagy
T14489	Azvudine	FNC,RO-0622	HCV Protease , HBV , HIV Protease , Reverse Transcriptase
	Azvudine (FNC) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine inhibits NRTI-resistant viral strains. Azvudine exerts highly potent inhibition on HIV-1...		HCV Protease , HBV , HIV Protease , Reverse Transcriptase
T7745	Diclofensine hydrochloride	Ro 8-4650 hydrochloride	Others , Dopamine Receptor
	Diclofensine hydrochloride (Ro 8-4650 hydrochloride) is a Novel Antidepressant, on Peripheral Adrenergic Function		Others , Dopamine Receptor
T19706	Ro 20-1724	Ro-20-1724,4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone,Ro20-1724	PDE
	Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.		PDE
T1488L	Procarbazine free base	CB 400-497,NSC-77213,Ro 4-6467/1,Ro 4-6467,Procarbazine
	Procarbazine is an antineoplastic chemotherapy drug for the treatment of Hodgkin's lymphoma and certain brain cancers. The drug is metabolized and activated in the liver. It also inhibits MAO thus increasing the effects ...
T13031	Sulfamethoxazole-d4	Ro 4-2130 D4	Others
	Sulfamethoxazole D4 is a deuterium labeled Sulfamethoxazole (Ro 4-2130). Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic.		Others
T11679	Isavuconazole-d4	BAL-4815 D4,RO-0094815 D4,Isavuconazole D4	Others
	Isavuconazole D4 is a deuterium labeled Isavuconazole. Isavuconazole is a triazole prodrug with antifungal activity against yeasts, molds, and dimorphic fungi.		Others
T12718	RG7800 hydrochloride (1449598-06-4 free base)	RO6885247 hydrochloride,RG7800 hydrochloride	Others
	RG7800 hydrochloride is an orally active modulator of SMN2 splicing.		Others
T6312	R547	Ro 4584820	Apoptosis , GSK-3 , PKA , CDK
	R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1.		Apoptosis , GSK-3 , PKA , CDK
T28595	Ro-0505124	Ro0505124,Ro 0505124
	Ro-0505124 is a potent, selective and ATP-competitive inhibitor of cyclin-dependent kinase 4 (CDK4).
T70838	RO27-3225 TFA
	RO27-3225, also known as RO273225 is a melanocortin type 4 receptor agonist with EC50 = 1 nM. It may alleviate intestinal dysfuntion and brain damage. It has been investigated for an anti-obesity medication. Ro 27-3225...